Firstly, pores form on the cells causing them to spill out. The water, Glycerol and fatty acids move into the interstitial space beneath the fatty layer in the skin. Then further water, fatty acids and Glycerol spill out.
The adipocyte cells reduce in size. This disruption does not affect the neighboring structures such as the skin, blood vessels or nerves. The lymphatic system then removes the fat through the liver and kidneys, where they are processed in the same way as fatty foods, the rest is passed out in the urine.